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San Jose[A] (/ˌsæn hoʊˈzeɪ, -ˈseɪ/; Spanish for 'Saint Joseph'; Spanish: [saŋ xoˈse]), officially the City of San José,[B] is an economic, cultural and political center of Silicon Valley, and the largest city in Northern California (both in population and area). With an estimated 2017 population of 1,035,317, it is the third-most populous city in California (after Los Angeles and San Diego) and the tenth-most populous in United States. Located in the center of the Santa Clara Valley, on the southern shore of San Francisco Bay, San Jose covers an area of 179.97 square miles (466.1 km2). San Jose is the county seat of Santa Clara County, the most affluent county in California and one of the most affluent counties in the United States. San Jose is the most populous city in both the San Francisco Bay Area and the San Jose-San Francisco-Oakland Combined Statistical Area, which contain 7.7 million and 8.7 million people respectively.